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Muscle Knots That Keep Coming Back? Understanding Myofascial Pain and Trigger Point Injections

Sep 21, 2026

Pain Management

trigger point injection trigger point injection

Most people have experienced a “knot” in a muscle at some point. You may notice a tight, tender spot in your neck after hours at a computer, an aching area between the shoulder blades, or a painful spot in your lower back that keeps returning. Sometimes massage, stretching, heat, or rest takes care of the problem. Other times, the same painful knot comes back again and again.

When muscle pain becomes persistent or keeps returning, the problem may be myofascial pain. A painful area within a tight band of muscle is often called a myofascial trigger point.

Trigger points are commonly associated with neck, shoulder, upper back, and lower back pain. They can also develop in other muscles throughout the body. Understanding why these painful areas develop is an important first step toward choosing the right treatment.

What Is a Muscle Knot?

The term “muscle knot” is not a precise medical diagnosis. Most people use it to describe a small area of muscle that feels unusually tight, firm, or tender.

Doctors often refer to these sensitive areas as trigger points. A trigger point is typically identified as a particularly tender spot within a tight band of muscle. Pressing on it may reproduce the pain you have been experiencing. Sometimes the pain stays right around the tender spot. In other cases, it can be felt somewhere nearby. This is called referred pain.

For example, a trigger point in a neck or shoulder muscle may cause pain around the shoulder or contribute to discomfort felt toward the head. Trigger points can also be associated with stiffness and difficulty comfortably moving the affected area.

Researchers are still studying exactly what happens within these painful areas, and the biology of trigger points is more complicated than simply having a muscle that is “stuck in a knot.” What we do know is that painful trigger points are recognized clinically and can develop as part of a condition called myofascial pain.

What Causes Muscle Knots and Trigger Points?

There is not always one clear cause. Trigger points may appear after an injury, repetitive strain, or prolonged stress on a muscle. In some people, several factors contribute at the same time.

Common contributors can include:

  • Repetitive movements at work or during exercise
  • Muscle overuse or an increase in physical activity
  • Prolonged sitting or working in one position
  • Poor body mechanics
  • Muscle strain or previous injury
  • Weakness or imbalance between muscle groups
  • Limited movement or reduced flexibility
  • Ongoing neck, back, or joint problems

In some cases, there is no obvious event that explains why the pain started.

This is one reason an examination can be important when a painful “knot” keeps returning. Not every neck or back pain is coming from muscle. Pain can also arise from joints, discs, nerves, or other structures. Different causes of pain require different treatments.

What Is Myofascial Pain?

“Myofascial” refers to muscle and the connective tissue surrounding it. Myofascial pain is pain involving these tissues, often accompanied by one or more tender trigger points.

The discomfort is often described as deep, aching, tight, or sore. It may be present much of the time, or it may worsen with certain movements, positions, or activities.

During an evaluation, the physician will ask about the location and pattern of your symptoms and examine the painful region. Pressing on a trigger point may reproduce the pain that brought you to the office.

That last part can be particularly helpful. If pressure on a specific area recreates your familiar pain, it provides information about whether the muscle is contributing to your symptoms.

Why Doesn't the Knot Just Go Away?

Many episodes of muscle pain do improve with time. Stretching, exercise, massage, physical therapy, activity changes, and other conservative treatments may all be helpful and are often an important part of treatment.

The difficulty occurs when the pain repeatedly returns despite these efforts.

In that situation, repeatedly treating the sore spot at home may provide temporary relief without answering a more important question: Why does this area keep becoming painful?

A recurring muscle problem may be related to how you move, repetitive stress, an underlying spine or joint problem, or another source of pain. Myofascial pain can also exist alongside other conditions.

That is why treatment is not simply about “getting rid of the knot.” The goal is to determine what is generating the pain and develop a treatment plan that addresses the individual problem.

What Is a Trigger Point Injection?

A trigger point injection is a procedure used to treat certain painful trigger points.

Unlike an epidural or facet procedure, a trigger point injection targets the painful muscle itself. After the physician identifies the appropriate trigger point, a small needle is carefully placed into that area.

Depending on the patient's condition and the treatment plan, a trigger point injection may involve a local anesthetic. Some needling techniques do not use medication at all. The appropriate approach depends on the individual patient.

The purpose of the procedure is to target the painful area of muscle directly. Trigger point injections are generally considered as one part of a broader treatment plan rather than a replacement for exercise, rehabilitation, or addressing the factors contributing to the muscle pain.

What Should I Expect During a Trigger Point Injection Visit?

The first and most important step is the evaluation.

Before recommending an injection, we want to determine whether the pain truly appears to be coming from a trigger point. Your physician will review your symptoms and examine the painful area. Depending on your symptoms and medical history, other potential causes of pain may also need to be considered.

If a trigger point injection is appropriate, the procedure itself is generally straightforward. The skin over the treatment area is cleaned, the trigger point is identified, and a small needle is placed into the targeted muscle. More than one trigger point may be treated when appropriate.

You may feel pressure, a brief pinch, or temporary discomfort as the needle enters the muscle. Occasionally, the muscle may briefly twitch when the trigger point is reached.

Some patients experience temporary soreness at the injection site afterward. Your physician will provide instructions based on the specific procedure performed and your individual medical situation.

The amount and duration of relief vary from person to person. Trigger point injections are not a guaranteed cure, and research continues to examine which patients receive the greatest benefit. For persistent myofascial pain, injections are often considered after simpler treatments have not provided adequate relief.

How Is a Trigger Point Injection Different From a Facet Injection?

This distinction is important because both treatments may be used for neck or back pain, but they target different sources of pain.

A trigger point injection targets a painful area within a muscle.

A facet procedure targets small joints in the spine, or the nerves that carry pain signals from those joints. Facet joints are located along the back of the spine and can be a source of neck or lower back pain.

A person can have muscle pain, facet-related pain, or a combination of both. An examination and, when appropriate, additional diagnostic information help determine which treatment makes sense.

Simply having neck or back pain does not automatically mean that either type of injection is appropriate.

How Is a Trigger Point Injection Different From an Epidural Injection?

An epidural injection has another purpose.

Epidural injections place medication into the epidural space around the spinal nerves. They may be considered for certain conditions in which spinal nerves are irritated or inflamed, particularly when symptoms travel into an arm or leg.

The difference can be summarized simply:

  • Trigger point injection: targets muscle
  • Facet procedure: targets pain arising from spinal joints or the nerves supplying those joints
  • Epidural injection: targets the area around spinal nerves

These procedures are therefore not interchangeable. Choosing the right procedure starts with determining the most likely source of the pain.

Should I Try Massage or Stretching First?

For many people, yes. Massage, stretching, appropriate exercise, and physical therapy can be useful treatments for myofascial pain. Less invasive approaches are generally tried before injections when appropriate.

If a muscle becomes sore after an unusually difficult workout and improves over several days, an injection is unlikely to be the first consideration.

A different situation is a knot that has been bothering you for weeks or months, frequently returns, limits your activity, or does not improve despite reasonable conservative treatment. At that point, simply stretching harder or scheduling another massage may not address the entire problem.

An evaluation can help determine whether you have a persistent trigger point, whether something else is causing the symptoms, and whether treatment should include physical therapy, changes in activity or movement, a trigger point injection, or another approach.

Do Trigger Point Injections Work for Everyone?

No treatment for muscle pain works for everyone. Trigger point injections are no exception.

Studies have produced mixed results, and research has not shown that one injected medication is always superior. Some patients experience meaningful short-term improvement, while others experience little or no benefit. This is why trigger point injections should be used selectively rather than as a routine treatment for every muscle knot.

The best approach to ongoing myofascial pain is usually a combined treatment plan. Reducing pain can be helpful, but long-term management may also require improving strength, flexibility, movement patterns, ergonomics, or other factors that contribute to repeated muscle irritation.

When Should I Have Recurring Muscle Knots Evaluated?

Consider an evaluation when pain:

  • Keeps returning in the same area
  • Persists despite stretching, massage, or activity changes
  • Limits exercise, work, sleep, or everyday activities
  • Is accompanied by ongoing neck or back pain
  • Spreads beyond the original painful area
  • Has not responded to physical therapy or other conservative treatment

An evaluation does not automatically mean that you need an injection. In fact, determining that another treatment would be more appropriate can be just as valuable.

Treat the Source, Not Just the Sore Spot

A massage or stretching session can feel very good when a muscle is tight and painful. For many minor episodes, that may be all that is needed.

But a muscle knot that continually returns deserves a closer look.

The important question is not simply, “How do I loosen this knot?” It is “Why does this pain keep coming back, and what is the best way to treat it?”

A careful evaluation can help distinguish myofascial pain from pain originating in the joints, discs, nerves, or other structures. When a persistent trigger point is part of the problem, a trigger point injection may be one option within a broader treatment plan designed to improve pain and function.

If recurring muscle knots, neck pain, shoulder pain, or back pain are interfering with your daily activities, consider scheduling an evaluation. Together, we can identify the likely source of your symptoms and discuss treatment options that fit your individual condition.

Get Help for Recurring Muscle Pain

If recurring muscle knots, neck pain, shoulder pain, or back pain are making it harder to work, exercise, sleep, or enjoy your daily activities, an evaluation can help determine what may be causing your symptoms.

At Maasumi Headache & Spine Care, we can evaluate your symptoms, identify potential sources of pain, and discuss treatment options that fit your individual condition.

Schedule an appointment to take the next step toward understanding and managing your recurring muscle pain.

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